The rate of death from any cause was 3.6% a year for people who took Pradaxa compared with 4.1% a year for people who took warfarin. In one study, Pradaxa was compared with the drug warfarin (Coumadin). Blood clots can be very serious, and PEs or DVTs can sometimes result in death, so it’s very important to try to prevent them from occurring. EffectivenessĬlinical studies looked at how well Pradaxa works to help prevent blood clots in people with nonvalvular A-fib. You’ll usually take the drug once or twice a day. Pradaxa comes as a capsule that you swallow. (A class of drugs is a group of medications that work in a similar way.) Pradaxa is a type of anticoagulant. Pradaxa contains the active drug dabigatran, which belongs to the drug class called direct thrombin inhibitors. Prevent DVTs and PEs in adults who have had a hip replacement.Decrease the risk of DVTs and PEs in adults and VTEs in children ages 8 though 17 years who have already received treatment for them.Treat VTEs in children ages 8 though 17 years who have taken an anticoagulant in injection form for at least 5 days.(Anticoagulants are sometimes called blood thinners.) Treat DVTs and PEs in adults who have taken a type of drug called an anticoagulant in injection form for 5 to 10 days.“Nonvalvular” means that faulty heart valves aren’t causing the condition. This is an irregular heartbeat in the upper chambers of your heart. Decrease the risk of stroke and blood clots in adults with nonvalvular atrial fibrillation (A-fib).These conditions are sometimes grouped together and called venous thromboembolisms (VTEs). And a blood clot in your lungs is called a pulmonary embolism (PE). It’s FDA-approved to decrease your risk of developing a blood clot, which can be dangerous if it’s in your legs or lungs.Ī blood clot that develops in your lower legs is typically known as a deep vein thrombosis (DVT). Pradaxa is a brand-name prescription medication.

Praxbind mechanism of action